Danazol in Idiopathic Thrombocytopenic Purpura

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منابع مشابه

Danazol in non-splenectomized patients with refractory idiopathic thrombocytopenic purpura.

Seven non-splenectomized patients with chronic refractory idiopathic thrombocytopenic purpura were treated with danazol 800 mg daily. All were glucocorticoid failures and four were refractory to all additional previous therapy. Five patients benefited from danazol and in two sustained normal platelet counts, for over 44 and 51 months, were observed. We conclude that danazol is useful for long t...

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Epidemiology of Idiopathic Thrombocytopenic Purpura in Children

Abstract Background Immune thrombocytopenic purpura (ITP) is a common autoimmune bleeding condition in children that is characterized by a decrease in the platelet count. The aims of this study were to define epidemiologic features of patients with primary ITP who were admitted to Mofid Children's Hospital, Tehran, Iran, in a 5-year period. Methods We retrospectively studied the records of ...

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Idiopathic thrombocytopenic purpura.

Idiopathic thrombocytopenic purpura in children usually a self limiting disorder. It may follow a viral infection or immunisation and is caused by an inappropriate response of the immune system. About 20-30% of children will fail to remit over six months (chronic idiopathic thrombocytopenic purpura). This is more likely in older children, especially girls. The disease is reviewed with reference...

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Idiopathic thrombocytopenic purpura in children

Idiopathic thrombocytopenic purpura (ITP) is the most common acquired bleeding disorder in childhood. ITP is characterized by a lo� circulating platelet count caused principally by destruction of antibody-coated platelets in the reticuloendothelial system. It can be classified into t�o major forms, acute and chronic. Acute ITP is usually a benign self-limiting condition �ith a high probability ...

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Idiopathic thrombocytopenic purpura in childhood.

Purpura is a relatively common symptom in childhood and may be due to a variety of causes. A platelet count enables one to exclude the nonthrombocytopenic variety, but more elaborate investigations are needed to exclude other primary conditions which are often associated with thrombocytopenia, e.g. leukaemia. There remains a group of patients with idiopathic thrombocytopenic purpura and it is w...

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ژورنال

عنوان ژورنال: Acta Haematologica

سال: 1985

ISSN: 0001-5792,1421-9662

DOI: 10.1159/000206184